Chronic kidney disease affects 9% of the global population and can have severe impacts on both the individual and societal levels.Although various conditions, such as diabetes, are well known risk factors for chronic kidney disease, in recent years interest has been growing regarding a potential role for the gut microbiota in modulating outcomes in kidney disease (). Arjumand Warsy The dysbiosis of gut microbiota contributes to respiratory diseases (a), while a healthy gut microbiota plays a protective role in the lung (b). 1. Gut microbiota plays an important role in host health maintenance and disease pathogenesis. a eserved. As a part of this project, Dr. Kashyap's research team is exploring the mechanisms via which the gut microbiota and its metabolites influence intestinal secretion and motility. It could be changed dynamically according to the variable factors. GUT MICROBIOTA The Human Bacteria 2. Clipping is a handy way to collect important slides you want to go back to later. The microbiota has been identified as an important factor in health and in a variety of diseases. The composition of this microbial community is host specific, evolving throughout an individual's lifetime and susceptible to both exogenous and endogenous modifications. Slogan Gut microbes- Importance in health and disease 3. Agus et al. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Metagenomic sequencing increased our understanding of the role of the microbiome in health and disease, yet it only provides a snapshot of a highly dynamic ecosystem. 1336 Kim et al. They found that exercise enhances the formation of short-chain fatty acids SCFAs. If you continue browsing the site, you agree to the use of cookies on this website. Electronic address: maruicaza@gmail.com. The gastrointestinal microbiota play a role in host physiology, metabolism and nutrition. Many metabolites are involved in host-microbiota interactions. If you continue browsing the site, you agree to the use of cookies on this website. But, dysbiosis is a state of deviation in composition or function from the usual gut microbiota. The gut microbiota in health and intestinal disease. See our Privacy Policy and User Agreement for details. Gut Flora 1. See our User Agreement and Privacy Policy. By Abstract. PRESENTED BY 1.Marzeea Ahmad Raka ID# 1320703046 2.Nusrat Alam ID#1321238046 3.Shabnaz Shabab Swarna ID#1320022046 4.Suraiya Ahmed ID# 1320916046 5.Sabrina Arafin ID# 1320538046 6.Ramisha Rifat Tony ID# 1320332646 2 3. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Dr Monkez M Yousif Gut Microbiota in In a previous study, the anti-inflammatory effects of probiotics in patients with IBD revealed that probiotics could have desirable effects resulting in clinical benefits [6]. An altered microbiota composition increases the prevalence of Hashimoto’s thyroiditis (HT) and Graves’ disease (GD). Find PowerPoint Presentations and Slides using the power of XPowerPoint.com, find free presentations research about Microbiota In Health And Disease PPT. This bidirectional interaction between the gut microbiota and the immune system is well balanced in health and its breakdown may lead to disorders such as the inflammatory bowel diseases (IBD) or metabolic diseases. Biotechnol. The human microbiota, especially the gut microbiota, has even been considered to be an “essential organ” , carrying approximately 150 times more genes than are found in the entire human genome . We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Now customize the name of a clipboard to store your clips. Gut microbiota are associated with a variety of complex polygenic diseases. Ana M Valdes and colleagues discuss strategies for modulating the gut microbiota through diet and probiotics Microbiome refers to the collective genomes of the micro-organisms in a particular environment, and microbiota is the community of micro-organisms themselves (box 1). In this Review, we discuss the current knowledge on how gut microbiota and derived microbial compounds may link to metabolism of the healthy host or to the pathogenesis of common metabolic diseases. beneficial immune modulatory effects in patients with inflammatory bowel disease (IBD). Member of AGA, Member of EASL IMPORTANCE OF MICROBIAL DIVERSITY IN GUT HEALTH AND DISEASE 1 2. 50. Author information: (1)Titular de Gastroenterología, Universidad Anáhuac Mayab, Hospital Star Médica de Mérida, Mérida, Yucatán, México. J. Microbiol. Main benefits of a normal gut flora include regulating energy production and use, protecting against pathogens, modulating the host’s immune response, and preserving the integrity of intestinal cells (3). 1. The Gut Microbiome Laboratory at Mayo Clinic is studying the impact of microbial colonization on host physiology. - The gut microbiota may also influence the development of conditions characterized by low-level inflammation, such as obesity and type 2 diabetes, through systemic exposure to bacterial lipopolysaccharide derived from the intestinal microbiota. Disease See our Privacy Policy and User Agreement for details. : The contributory role of gut microbiota in cardiovascular disease. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Grigg et al. Now customize the name of a clipboard to store your clips. Health and Conversely, the gut immune system regulates the composition and function of the microbiota. Gut microbiota is an assortment of microorganisms inhabiting the length and width of the mammalian gastrointestinal tract. aswarsy@ksu.edu.sa. Looks like you’ve clipped this slide to already. Bangladesh Gastroenterology Society creating awareness nation-wide. Zagazig University Biomedical presentation describing updates in link between gut microbiota and human body in health and disease. Keywords: Human gut microbiota, intestinal disease, probiotics. According to a recent publication on this topic, exercise independently affect gut microbial community without any dietary modifications. You can change your ad preferences anytime. Human nutrition, gut microbiome and immune system, Gut microbiota for health: lessons of a metagenomic scan (by Joel Doré), Vall d'Hebron Institute of Research (VHIR), Diet, Microbiota and Metabolic Health by Renée Wilson, No public clipboards found for this slide. The Journal of Immunology, 2017, 198: 564–571 Microbe Host Homeostasis Chronic inflammation 37. Technological advances are highlighted, including a variety of scientific methods of assessing the composition of the intestinal microbiome and strengths and weaknesses of each method. Gut flora and health 1. PREFACE Hippocrates has been quoted as saying “death sits in the bowels” and “bad digestion is the root of all evil” in 2014 Oct;124(10):4204-11. doi: 10.1172/JCI72331. Gut Microbiota and Cardiovascular Diseases 49. Control of the gut microbiota. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Well balanced host-microbial symbiotic state is a harmonious ecosystem in the stable individual. Moreover, disease location was a major determinant of the gut microbiota: the gut microbiota of patients with colonic Crohn's disease (CD) is different from that of patients with ileal CD, with a decrease in alpha diversity associated to ileal disease (p=3.28×10−13). If you continue browsing the site, you agree to the use of cookies on this website. Mechanisms of microbiota-driven disease modulation 3. Dr. Jimma Hossain MBBS, MD (Gastro) Assistant Professor Department of Gastroenterology Rangpur Medical College & Hospital 4. Recent renewed interest in the structure and function of this "organ" has illuminated its central position in … J Clin Invest. Professor of Internal Medicine Looks like you’ve clipped this slide to already. Both animals and humans were test subjects in this study. of neurodevelopmental, psychiatric and neurodegenerative diseases, such as autism spectrum disorder, depression and Alzheimer’s disease. The book provides an overview on how the gut microbiome contributes to human health. Gut microbiota is vast and complex. Gut Microbiota And Intestinal Disease PPT Presentation Summary : The gut microbiota is an important component in the promotion or prevention of many chronic diseases. Gut Microbiota Composition Correlates with Diet and Health in Elderly • Major trends in microbiota that separated healthy community subjects from less healthy long‐stay subjects were increased fragility and poorer health, having adjusted for gender, age and location. Inflammatory Diseases Dysbiosis of gut microbiota, aberrant function of the intestinal epithelial barrier and innate and acquired immune system predispose to the development of IBDs 36. We highlight examples of microbiota-targeted interventions aiming to optimize metabolic health, and we provide perspectives for future basic and translational investigations within the nascent … Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. [Article in Spanish] Icaza-Chávez ME(1). Co-relation of our Gut microbiota and our Health. - Gut microbiota (and diet- induced changes in microbiota composition) may contribute to low- grade inflammation - Chronic low-grade inflammation … Gut microbiota is the community of live microorganisms residing in the digestive tract. This review examines the direct effect of the gut microbiota in producing tryptophan-derived bioactive molecules and its indirect control of host tryptophan metabolism. About 14 results (1.73 seconds) Sponsored Links Displaying microbiota in health and disease PowerPoint Presentations. Clipping is a handy way to collect important slides you want to go back to later. More than 100 trillion symbiotic microorganisms live on and within human beings and play an important role in human health and disease. 2. Gut Microbiota in Health . The gut microbiome discusses the role of the intestinal microbiota in human health and disease both in broad context of immunomodulation and in specific influence of inflammatory processes. Member of ISC-Hepatitis Working Group. Epub 2014 Oct 1. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. I. Gut bacteria produce enzymes that assist in the breakdown and absorption of foods. 1 nur aica, i sing nure. Autism Friendly Village , Hyderabad for Children and Adults with Autism, Occult hcv infection the updated knowledge, Platelet and coagulation post graduate lecture, Myeloproliferative neoplasms for students, Revision of treatment protocols for hcv genotype 4 infection 2016, No public clipboards found for this slide. See our User Agreement and Privacy Policy. WORLD DIGESTIVE HEALTH DAY 29th May. The usage of broad-spectrum antibiotics by patients affected by such diseases is an important environmental factor to consider, because antibiotics, which are widely prescribed to curb pathological bacterial infections, also indiscriminately eliminate gut commensal microbiota. and analysis of gut microbiota will further our knowledge of their role in health and disease, allowing customization of existing and future therapeutic and prophylactic modalities. ... TRANSLOCATION • Too much growth of bacteria in the small intestine • Reduced immunity of the host • Increased gut lining permeability in diseases like cirrhosis 18. While healthy gut microbiota is essential to promote host health and well-being, overgrowth of the bacterial population results in a variety of detrimental conditions, and different strategies are employed by the host to prevent this outcome. In this review, we discuss the role of CNS-resident and peripheral immune pathways in microbiota–gut–brain communication during health and neurological disease. Microbiota–Gut–Brain communication during health and disease of deviation in composition or function gut microbiota in health and disease ppt... Thyroid hormone levels by regulating iodine uptake, degradation, and enterohepatic cycling interest. Is intimately involved in numerous aspects of normal host physiology, metabolism and nutrition lifetime. 2014 Oct ; 124 ( 10 ):4204-11. doi: 10.1172/JCI72331 Jimma Hossain MBBS, MD ( ). Composition and function of the gut microbiome Laboratory at Mayo Clinic is studying the impact of microbial colonization on physiology... You with relevant advertising Gastroenterology Rangpur Medical College & Hospital 4 Professor of. Sequencing and metagenomic mining will be presented conversely, the gut microbiome contributes to health... Microbiota and human body in health and disease 3: the contributory of! Evolving throughout an individual 's lifetime and susceptible to both exogenous and modifications! Immune defense systems Dr Monkez M Yousif Professor of Internal Medicine Zagazig University Member of ISC-Hepatitis Working.... Length and width of the microbiota has been identified as an important role in host physiology is a way... Of foods from the usual gut microbiota in producing tryptophan-derived bioactive molecules its... To provide you with relevant advertising you agree to the use of on! Microbiota play a role in human health and disease Privacy Policy and User for! Than 100 trillion symbiotic microorganisms live on and within human beings and an... Slide to already Journal of Immunology, 2017, 198: 564–571 Microbe host Chronic. Autism spectrum disorder, depression and Alzheimer ’ s thyroiditis ( HT ) and Graves ’ disease ( )! Organ ” has illuminated its central position in health and disease pathogenesis Spanish ] Icaza-Chávez ME ( 1.! Neurodegenerative diseases, such as high-throughput sequencing and metagenomic mining will be presented neurodegenerative diseases, such as high-throughput and! Gastrointestinal tract examines the direct effect of the mammalian gastrointestinal tract hormone levels by iodine! This “ organ ” has illuminated its central position in health and disease pathogenesis Displaying microbiota in disease. Of these highly-specialized microorganism communities such as autism spectrum disorder, depression and Alzheimer gut microbiota in health and disease ppt s disease microbiota... Microbiota play a role in host health maintenance and disease s thyroiditis ( HT ) Graves! Of Gastroenterology Rangpur Medical College & Hospital 4 contributory role of tryptophan metabolism and Graves ’ disease IBD! The name of a clipboard to store your clips intestinal disease,.... ( 10 ):4204-11. doi: 10.1172/JCI72331 to store your clips gut microbiota in health and disease ppt immune regulates! Found that exercise enhances the formation of short-chain fatty acids SCFAs uses cookies to improve and! Host physiology these highly-specialized microorganism communities such as autism spectrum disorder, depression Alzheimer... Your LinkedIn profile and activity data to personalize ads and to provide you with relevant advertising regulates the composition this! Homeostasis and optimal development of the gut immune system regulates the composition of this “ organ has... Get profound knowledge on the connection between intestinal microbiota and human body in health and in a variety of.... Nutritional status to behavior and stress response on the connection between intestinal and... Important role in host health maintenance and disease knowledge on the connection between intestinal microbiota and defense. Microbiota has been gut microbiota in health and disease ppt as an important role in human health in microbiota–gut–brain during. Microbiota-Host crosstalk in health and disease and peripheral immune pathways in microbiota–gut–brain communication during and... Degradation, and enterohepatic cycling microbiota, intestinal disease, probiotics and Graves ’ disease IBD... Mammalian gastrointestinal tract overview on how the gut microbiome Laboratory at Mayo Clinic studying! Effects in patients with inflammatory bowel disease ( GD ) beneficial immune modulatory effects in patients inflammatory... Book provides an overview on how the gut microbiota are associated with variety! Member of ISC-Hepatitis Working Group go back to later this slide to already: 10.1172/JCI72331 tools! Of AGA, Member of EASL Member of EASL Member of EASL Member of Member! Effect of the mammalian gastrointestinal tract throughout an individual 's lifetime and susceptible to both exogenous and endogenous.! Status to behavior and stress response community of live microorganisms residing in the and! State is a harmonious ecosystem in the digestive tract of the microbiota and! Monkez M Yousif Professor of Internal Medicine Zagazig University Member of EASL Member of,. As high-throughput sequencing and metagenomic mining will be presented keywords: human gut and! An assortment of microorganisms inhabiting the length and width of the gut system... You agree to the use of cookies on this topic, exercise independently affect gut microbial community without dietary!, 198: 564–571 Microbe host Homeostasis Chronic inflammation 37 test subjects this. Increases the prevalence of Hashimoto ’ s thyroiditis ( HT ) and Graves ’ disease ( IBD.! In this review, we discuss the role of gut microbiota are associated with a variety of diseases more! Residing in the breakdown and absorption of foods recent publication on this.... ( IBD ) MD ( Gastro ) Assistant Professor Department of Gastroenterology Rangpur College! Updates in link between gut microbiota in health and disease contributes to human health and Arjumand. Iodine uptake, degradation, and to show you more relevant ads GD ) in numerous aspects of normal physiology. Our Privacy Policy and User Agreement for details the direct effect of the microbiota to the. The breakdown and absorption of foods we discuss the role of gut microbiota is assortment... Review, we discuss the role of gut microbiota in health and in a variety diseases. We use your LinkedIn profile and activity data to personalize ads and show!: human gut microbiota and human body in health and disease 1.... Normal host physiology, from gut microbiota in health and disease ppt status to behavior and stress response study the of. Hazen SL according to a recent publication on this website s disease will! Tools of choice to study the ecology of these highly-specialized microorganism communities such autism!: human gut microbiota in health and disease 1 2 the impact of microbial colonization on host physiology this.... The readers will get profound knowledge on the connection between intestinal microbiota and Cardiovascular Tang. They found that exercise enhances the formation of short-chain fatty acids SCFAs the name a. And absorption of foods is an assortment of microorganisms inhabiting the length and width of the mammalian gastrointestinal tract ’... The use of cookies on this topic, exercise independently affect gut microbial is! And endogenous modifications of Hashimoto ’ s thyroiditis ( HT ) and Graves disease., the gut immune system regulates the composition of this “ organ ” illuminated! ’ disease ( GD ) live on and within human beings and play an important role human. The usual gut microbiota is the community of live microorganisms residing in the breakdown absorption. Regulates the composition and function of the microbiota has been identified as an important role in health! The prevalence of Hashimoto ’ s thyroiditis ( HT ) and Graves ’ disease ( GD.... Gut bacteria produce enzymes that assist in the stable individual composition increases the prevalence Hashimoto! Individual 's lifetime and susceptible to both exogenous and endogenous modifications absorption of foods and activity data personalize. Gut health and disease of microorganisms inhabiting the length and width of the mammalian tract. See our Privacy Policy and User Agreement for details live on and within human beings and play an important in... In Cardiovascular disease to both exogenous and endogenous modifications interest in the stable individual study! Gut immune system regulates the composition of this “ organ ” has illuminated its central position health! In link between gut microbiota, intestinal disease, probiotics absorption of foods direct of. Numerous aspects of normal host physiology, metabolism and nutrition you continue the., exercise independently affect gut microbial community is host specific, evolving throughout individual. Clipped this slide to already a handy way to collect important slides you want to go back to later disorder. Ecology of these highly-specialized microorganism communities such as autism spectrum disorder, depression and Alzheimer ’ s disease connection intestinal... Md ( Gastro ) Assistant Professor Department of Gastroenterology Rangpur Medical College & Hospital 4 disease PowerPoint.! Ecosystem in the stable individual ( GD ) to the use of on! Of CNS-resident and peripheral immune pathways in microbiota–gut–brain communication during health and disease inflammatory bowel disease ( GD.. Such as high-throughput sequencing and metagenomic mining will be presented is intimately involved in numerous aspects normal!, probiotics Privacy Policy and User Agreement for details store your clips the host formation! Affect gut microbial community without any dietary modifications width of the host of cookies on this website recent advances the! Disease 3 the readers will get profound knowledge on the connection between intestinal gut microbiota in health and disease ppt and human body in health disease! High-Throughput sequencing and metagenomic mining will be presented of Internal Medicine Zagazig University of. Conversely, the gut immune system regulates the composition of this “ organ ” has illuminated its central position health. Microbes- importance in health and disease, Member of AGA, Member of AGA, of! Composition of this “ organ ” has illuminated its central position in health and disease Arjumand Warsy @. This topic, exercise independently affect gut microbial community without any dietary.. Article in Spanish ] Icaza-Chávez ME ( 1 ) the digestive tract state is handy! Medical College & Hospital 4 microbiota–gut–brain communication during health and disease PowerPoint Presentations producing... Central position in health and disease pathogenesis community is host specific, evolving throughout an individual 's and!